Neutrogena Stubborn Acne Spot Drying Lotion — 10% Sulfur, 4% Niacinamide, 1 fl oz — Fragrance-Free Overnight Spot Treatment

Neutrogena Stubborn Acne Spot Drying Lotion is a fragrance-free, topical spot treatment formulated with 10% sulfur and 4% niacinamide to help dry and reduce the appearance of individual pimples.

This fast-acting spot lotion targets visible pimples and post-acne discoloration without added fragrance, dyes, parabens, phthalates or oils. Designed by a dermatologist-recommended brand, the lotion uses sulfur at the highest over-the-counter concentration to penetrate pores while niacinamide addresses dark marks. The formula also includes calming ingredients such as calamine and zinc oxide and is intended for targeted, overnight application.

How does this spot lotion work on a stubborn pimple?

The lotion combines sulfur, a traditional topical ingredient, with niacinamide and soothing minerals to help reduce the look of inflamed bumps. Applied as a thin layer with a cotton swab, the product dries on the surface to help shrink and visibly diminish pimples overnight.

• 10% sulfur to penetrate pores and help dry acne lesions
• 4% niacinamide to help target dark spots and uneven tone
• Calamine and zinc oxide to soothe redness and irritation
• Fragrance-, dye-, paraben-, phthalate- and oil-free formulation

When and how should I apply it for best results?

Use the spot lotion in the evening after cleansing and drying your skin. Dab a thin layer directly on the affected area with a clean cotton swab, avoid rubbing, let it dry, and leave it on overnight; rinse gently in the morning.

• Apply only to individual pimples, not to entire face
• Use a clean cotton swab for precise application
• Allow to dry; remove in the morning with warm water
• Pair with a daytime barrier like patches for all-day treatment

Is this safe for sensitive or acne-prone skin?

The fragrance-free, oil-free formula is designed with acne-prone skin in mind and omits common irritants such as parabens and phthalates. As with all active topical treatments, perform a patch test if you have very sensitive skin and discontinue use if irritation worsens.

• Formulated without fragrances, dyes, oils, parabens or phthalates
• Contains calming ingredients—calamine and zinc oxide
• Not intended for large-area application or broken skin
• Patch-test recommended for sensitive skin types

How does this fit into a daily skincare routine?

Use the drying lotion as a targeted PM step after your regular cleansing and treatment routine. Follow with sunscreen and any daytime serums the next morning; consider using a blemish patch in the AM for extended spot protection and to prevent picking.

• Cleanse first, then apply as a final targeted PM step
• Morning: rinse treated area, follow with moisturizer and SPF
• Complement with non-comedogenic moisturizers and sunscreen
• Combine with Stubborn Acne Blemish patches for 24-hour management

Who is this for: Neutrogena Stubborn Acne Spot Drying Lotion is intended for people with occasional inflamed or persistent pimples who want a targeted overnight treatment without fragrance or oils. It's suited for acne-prone skin that tolerates topical actives and for users seeking a concentrated sulfur option to help reduce the visible size and redness of isolated breakouts. Not recommended for children under the product instructions or for application on open wounds; consult a dermatologist for severe or widespread acne concerns.