Mary&May Spicule PDRN Duo Set — Retinol & Collagen Creams 0.53 oz ×2, micro‑spicule delivery and hydration

Mary&May Spicule PDRN Duo Set pairs a micro‑spicule retinol cream with a collagen‑rich PDRN cream to target texture, pores, and plumpness in alternating routines.

This two‑jar travel‑friendly set contains one 0.53 oz Retinol PDRN Cream and one 0.53 oz Collagen PDRN Cream, each formulated around marine‑derived micro‑spicules and PDRN (Sodium DNA). The pair was designed so you can alternate treatments: the Retinol formula focuses on the look of enlarged pores, fine lines, and uneven texture, while the Collagen formula prioritizes volume, elasticity, and a more supple appearance. Both include a comfort blend—panthenol, ceramide NP, sodium hyaluronate, and allantoin—to help maintain hydration and soothe skin after spicule use.

How should I use the Retinol and Collagen creams together in a routine?

Alternate the two creams rather than layering them: choose one product per evening. Start slowly—apply either formula 2–3 nights per week and increase frequency only if your skin tolerates it; do not combine both at once.

• Use Retinol PDRN at night for pores, lines, and texture concerns.
• Use Collagen PDRN on alternate nights to support plumpness and elasticity.
• Avoid pairing with strong AHAs/BHAs/PHAs or high‑strength vitamin C in the same routine.
• Always apply daily sunscreen while using retinol products.

What makes the Retinol PDRN Cream effective for pores and fine lines?

The yellow Retinol PDRN Cream combines 2,000 ppm marine‑derived micro‑spicules with 1,000 ppm nano‑liposome retinol to address the appearance of enlarged pores, fine lines, and uneven texture. Clinical evaluation targeted pore depth, area and density, eye‑area and smile lines, texture, and firmness for visible improvement trends.

• 2,000 ppm micro‑spicules for targeted delivery to the skin surface.
• 1,000 ppm nano‑liposome retinol for controlled retinol release.
• Clinical endpoints measured pore and line appearance plus texture and firmness.

How does the Collagen PDRN Cream support plumpness and elasticity?

The purple Collagen PDRN Cream blends 1,000 ppm micro‑spicules with 3,000 ppm hydrolyzed marine collagen and CICA PDRN to help improve skin volume, barrier condition, and elasticity at measured depths. It’s formulated to give a more supple look while the comfort blend helps reduce potential irritation from spicule use.

• 3,000 ppm hydrolyzed marine collagen for surface plumping effects.
• CICA PDRN (Sodium DNA) included for skin comfort support.
• Clinical checks focused on volume, barrier health, and elasticity.

Will the spicules feel uncomfortable, and is there fragrance?

Some users experience a temporary prickling or tingling sensation after applying formulas that contain micro‑spicules; this varies by individual and does not indicate better results. Both formulas are fragrance‑free and include a 4X comfort blend—2% panthenol, ceramide NP, sodium hyaluronate, and allantoin—to help hydrate and calm.

• Tingling is normal for some users, usually short‑lived.
• No added fragrance to minimize irritation risk.
• Comfort actives help support hydration and barrier feel after use.

Who is this for: The Mary&May Spicule PDRN Duo Set is aimed at people who want a targeted, alternating approach to surface texture and volume—suitable for those addressing visible pores, fine lines, and skin laxity while prioritizing controlled retinol use and skin comfort. It’s ideal for experienced retinol users and those ready to introduce micro‑spicule delivery; beginners should start slowly, monitor sensitivity, and always pair use with sunscreen during the day.

Ingredients

Aqua(Water), Methylpropanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Panthenol, Caprylic/Capric Triglyceride, Polypropylsilsesquioxane, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glyceryl Stearate, Cetyl Ethylhexanoate, Vinyl Dimethicone, Macadamia Ternifolia Seed Oil, Brassica Campestris (Rapeseed) Sterols, Polyglyceryl-10 Laurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12- 20 Alkyl Glucoside, Arginine, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Cholesterol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrolyzed Sponge, Polyisobutene, Gardenia Florida Fruit Extract, Tocopherol, Allantoin, Ethylhexylglycerin, Butyrospermum Parkii (Shea) Butter, Retinol, Xanthan Gum, Hydrogenated Lecithin, Sodium Hyaluronate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Adenosine, Dextrin, Helianthus Annuus (Sunflower) Seed Oil, Lauryl Glucoside, Polyglutamic Acid, Polyglyceryl-6 Laurate, Disodium EDTA, Ceramide NP, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Myristyl Glucoside, Stearic Acid, Benzotriazolyl Dodecyl p-Cresol, Glyceryl Acrylate/Acrylic Acid Copolymer, Oleic Acid, PVM/MA Copolymer, Beta-Carotene, Sodium DNA