Cetaphil Healthy Renew Night Face Cream 1.7 oz — peptide retinol-alternative, hydrates up to 48 hrs

Cetaphil Healthy Renew Night Face Cream is a dermatologist-recommended overnight treatment that helps reduce the appearance of fine lines while replenishing moisture and evening skin tone by morning.

This rich, restorative night cream combines a retinol alternative with purified peptides, niacinamide (vitamin B3) and panthenol (vitamin B5) to support skin renewal without the irritation commonly associated with stronger retinoids. Formulated for sensitive skin, it absorbs quickly, delivers long-lasting hydration, and targets dullness and uneven tone using botanical extracts such as rice lees and edelweiss. The product is fragrance-free, hypoallergenic and free from parabens, designed for nightly use to help skin appear smoother and more radiant.

How does this night cream reduce the look of fine lines?

The formula uses purified peptides — a gentler alternative to traditional retinol — to promote visible smoothing while minimizing irritation. Peptides support skin renewal processes and complement barrier-supporting ingredients to help skin appear firmer over time.

• Purified peptides as an effective retinol alternative for sensitive skin
• Clinically shown to visibly improve fine lines within weeks
• Does not require lengthy adaptation or increase sun sensitivity

Will this product work for sensitive or easily irritated skin?

Yes. The night cream is developed to be gentle: it is hypoallergenic, fragrance-free and dermatologist tested for use on sensitive skin. Barrier-supporting vitamins and soothing agents help defend against common sensitivity signs.

• Vitamin B3 (niacinamide) and B5 (panthenol) to hydrate and calm
• Formulated to reduce dryness, irritation, roughness and tightness
• Free from parabens and added fragrance to limit triggers

How long does hydration last and how quickly will I see results?

The lightweight yet rich cream absorbs efficiently and is formulated to provide extended moisture that can last up to 48 hours after application. Users may notice improved hydration immediately and visible reduction in the appearance of fine lines within a couple of weeks of nightly use.

• Fast-absorbing texture for comfortable overnight wear
• Hydrates for up to 48 hours for a refreshed morning appearance
• Visible smoothing reported in clinical use within weeks

What other skin concerns does it address besides wrinkles?

Beyond anti-aging benefits, this cream helps even out skin tone, reduce visible dullness and support the skin’s natural moisture barrier. Botanical extracts work alongside vitamins to target discoloration and leave skin looking more luminous.

• Rice lees and edelweiss extracts target uneven tone and dullness
• Barrier repair ingredients help protect against moisture loss
• Defends against five signs of sensitivity including weakened barrier

Who is this for: Cetaphil Healthy Renew Night Face Cream is intended for people seeking a sensitive-skin-friendly anti-aging treatment that combines hydration and visible smoothing. It suits those who want the benefits of peptide-based renewal without the harsher effects of traditional retinoids, and anyone looking to improve dullness, strengthen the skin barrier, and wake up to a more rested, luminous complexion. For best results, apply nightly as part of an evening skincare routine and pair with daytime sun protection.

Ingredients

Water, Glycerin, Propanediol, Panthenol, 1,2-Hexandiol, Niacinamide, C13-15 Alkane, Butyrospermum Parkii (Shea) Butter, Coco Nucifera (Coconut) Oil, Sodium Polyacryloyldimethyl Taurate, Hydrogenated Polydecene, Silica, Tocopheryl Acetate, Vinyl Dimethicone, C14-22 Alcohols, Leontopodium Alpinum Extract, Polyglyceryl-2 Stearate, Polyacrylate-13, C12-20 Alkyl Glucoside, Oryza Sativa (Rice) Lees Extract, Glyceryl Stearate, Stearyl Alcohol, Polyisobutene, Hydrolyzed Soy Flour, Adenosine, Dimethicone/Vinyl Dimehicone Crosspolymer, Butylene Glycol, Trisodium Ethylenediamine Disuccinate, Acacia Senegal Gum, Citric Acid, Agar, Caprylyl Glycol, Polysorbate20, Sodium Benzoate, Sorbitan Isostearatec, Potassium Sorbate, Sodium Hyaluronate, Xanthan Gum, Ethylhexylglycerin, Buddleja Davidii Extract, Thymus Vulgaris (Thyme) Extract