NUVADERMIS 40% Urea Cream for Rough, Dry Skin — 8 oz Intensive Moisturizer for Heels, Calluses & Feet

NUVADERMIS 40% Urea Cream is an intensive, fast-absorbing moisturizer formulated to soften extremely dry, cracked skin, heels, calluses and rough patches on the body.

If your skin struggles with thickened, rough areas—especially on feet, heels, elbows and knees—this high-concentration urea lotion combines keratolytic action with deep hydration to improve texture and comfort. The rich, non-greasy formula blends 40% urea with supportive moisturizing ingredients and salicylic acid to help loosen hardened skin while drawing and retaining moisture for lasting softness.

How quickly will I notice softer skin after using this 40% urea cream?

Many users feel the difference after the first application as the cream delivers intense moisturization and begins to soften rough patches. Noticeable texture improvement typically occurs after repeated nightly use over several days to weeks, depending on severity.

• Immediate hydration and reduced tightness after one use
• Improved smoothness with consistent daily/nightly application
• Best results when used on clean, dry skin and under socks for feet

Can this cream help with thick calluses and cracked heels?

Yes—this formulation combines a high urea concentration with salicylic acid to help loosen and reduce hardened layers while replenishing moisture. It’s designed to reduce roughness without aggressive scrubbing, making the process gentler on delicate skin.

• Urea 40% helps break down excess keratin in calluses
• Salicylic acid supports gentle exfoliation of hardened areas
• Thick texture targets problem zones yet absorbs without greasy residue

How should I use NUVADERMIS 40% Urea Cream safely and effectively?

Apply a thin layer to affected areas once or twice daily, or as tolerated, avoiding open wounds and mucous membranes. For best results on feet, apply at night, cover with socks, and maintain regular use until skin texture improves.

• Use on clean, dry skin; do not apply to broken skin
• Start with once daily to assess tolerance, increase if needed
• Keep out of eyes and avoid sun-exposed broken areas after application

What makes this formulation different from regular moisturizers?

This product contains a clinical-strength 40% urea concentration paired with salicylic acid and humectants that both exfoliate and replenish moisture. The result is targeted treatment for very dry, thickened areas rather than general daily body hydration.

• High urea concentration for keratolytic and humectant effects
• Salicylic acid to support gentle exfoliation of roughened skin
• Rich but fast-absorbing texture designed for feet, hands, elbows, knees

Who is this for: NUVADERMIS 40% Urea Cream is intended for people with very dry, rough, or callused skin who want a concentrated topical treatment to soften and smooth problem areas. It’s suitable for use on feet, heels, elbows, knees, and other thickened patches when used as directed; it is dermatologist-tested and cruelty-free, but not for use on open wounds or by anyone advised to avoid keratolytic agents.