NIOXIN System 2 Shampoo & Conditioner Liter Duo — 2 x 1L with Pumps for Thinning Hair, Cleansing + Lightweight Conditioning

This two-piece liter duo delivers the first two steps of NIOXIN's System 2: a deep-cleansing Cleanser Shampoo and a lightweight Scalp Therapy Conditioner, each supplied with pumps for easy salon-style dispensing. Built on the brand’s Activ-Renewal and AMP technologies, the set targets excess sebum and residue while restoring moisture balance to leave hair looking fuller and more resilient. The formulas are developed from NIOXIN’s 30 years of thinning-hair expertise and are intended to be used as part of the full three-step system for best results.

How does the System 2 shampoo prepare the scalp for thicker-looking hair?

The Cleanser Shampoo uses Activ-Renewal technology to remove sebum, fatty acids and styling residue that can build up on the scalp and hair. By clearing these impurities, the scalp environment becomes more receptive to treatments and styling, helping hair appear thicker and less weighed down.

• Deep-cleansing action removes oil and product buildup
• Prepares scalp for subsequent topical treatments
• Maintains hair movement without heavy residue

What benefits does the System 2 conditioner provide for progressed thinning?

The Scalp Therapy Conditioner is lightweight but moisture-balancing, formulated to strengthen hair resilience and protect amplified hair structure. It helps detangle, improve manageability and support a fuller appearance without adding weight.

• AMP technology helps reinforce hair structure
• Restores hydration while keeping hair airy and touchable
• Reduces breakage by improving hair pliability

How quickly can users expect to notice changes in hair thickness and density?

Consumer feedback and clinical observations indicate visible improvements in as little as 30 days when the full regimen is followed consistently. Results vary by individual, but the System 2 duo is formulated to deliver progressive visual changes in thickness, density and fullness over continued use.

• Noticeable visual changes reported in ~30 days for many users
• Best outcomes seen when used with NIOXIN’s third-step topical treatment
• Consistency and correct application improve results

Can this duo be used on color-treated or natural hair?

System 2 is created for natural hair with progressed thinning, but the gentle formulation is compatible with many color-treated routines. It focuses on scalp health and structural support, preserving manageability while addressing thinning-related concerns.

• Designed for natural hair with progressed thinning
• Suitable in many color-care regimens when used as directed
• Pumps included for controlled, mess-free dispensing

Who is this for: NIOXIN System 2 Liter Duo is aimed at people with natural, untreated hair experiencing progressed thinning who want a salon-grade cleansing and conditioning pair to improve scalp clarity and the visual thickness of hair. It’s ideal for daily or frequent use as the first two steps of NIOXIN’s three-part protocol, and for anyone seeking larger, pump-dispensed bottles for home or professional use.

Ingredients

Shampoo: WATER/EAU, SODIUM LAURETH SULFATE, SODIUM LAURYL SULFATE, COCAMIDOPROPYL BETAINE, SODIUM CITRATE, SODIUM XYLENESULFONATE, SODIUM CHLORIDE, COCAMIDE MEA, SODIUM BENZOATE, CITRIC ACID, SALICYLIC ACID, MENTHA PIPERITA (PEPPERMINT) OIL, MENTHA ARVENSIS LEAF OIL, MENTHOL, TETRASODIUM EDTA, SODIUM HYDROXIDE, METHYLPARABEN, PROPYLENE GLYCOL, CAMELLIA SINENSIS LEAF EXTRACT, CYSTINE BIS-PG-PROPYL SILANETRIOL, BIOTIN, LECITHIN, NIACINAMIDE, PANTHENOL, TOCOPHERYL ACETATE, CITRUS PARADISI (GRAPEFRUIT) PEEL EXTRACT, HUMULUS LUPULUS (HOPS) FLOWER EXTRACT, URTICA DIOICA (NETTLE) LEAF EXTRACT, YELLOW 5, YEAST EXTRACT/EXTRAIT DE LEVURE, ACER SACCHARUM (SUGAR MAPLE) EXTRACT, CITRUS LIMON (LEMON) PEEL EXTRACT, SACCHARUM OFFICINARUM EXTRACT, VACCINIUM MYRTILLUS LEAF EXTRACT, BLUE 1, CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT, RED 33, POTASSIUM SORBATE. Conditioner: Aqua/Water/Eau, Cetyl Alcohol, Stearamidopropyl Dimethylamine, Stearyl Alcohol, Quaternium-18, Phenoxyethanol, Benzyl Alcohol, Cetearyl Alcohol, Hydroxypropyl Guar, Glyceryl Stearate, Hydroxyethylcellulose, Oleyl Alcohol, Methylparaben, Propylparaben, Polysorbate 60, Mentha Piperita (Peppermint) Oil, Mentha Arvensis Leaf Oil, Menthol, EDTA, Propylene Glycol, Citric Acid, Camellia Sinensis Leaf Extract, Cystine Bis-PG-Propyl Silanetriol, Biotin, Lecithin, Niacinamide, Panthenol, Tocopheryl Acetate, Citrus Paradisi (Grapefruit) Peel Extract, Humulus Lupulus (Hops) Flower Extract, Urtica Dioica (Nettle) Leaf Extract, Acer Saccharum (Sugar Maple) Extract, Citrus Limon (Lemon) Peel Extract, Saccharum Officinarum/Sugar Cane Extract/Extrait de canne à sucre, Vaccinium Myrtillus Leaf Extract, Faex Extract/Yeast Extract/Extrait de levure, Citrus Aurantium Dulcis (Orange) Fruit Extract, Potassium Sorbate, Sodium Benzoate, Blue 1 (CI 42090), Maltodextrin, Ethylparaben, Butylparaben